Immunosuppressant / Transplant Medicine
mycophenolate malate tablet
Description :
Mycophenolate is an immunosuppressive medication used to prevent the body from rejecting a transplanted kidney, heart, or liver. It works by suppressing the activity of the immune system, specifically inhibiting lymphocyte proliferation, thereby reducing the risk of organ rejection.
It may also be prescribed in certain autoimmune diseases (such as lupus nephritis) when other treatments are not effective.
---
Dosage:
Adults (Transplant):
Typical starting dose: 1g twice daily (2000mg total) in divided doses, depending on the formulation (Mycophenolate mofetil or sodium).
Dosage must be individualized by a healthcare professional.
Always taken on an empty stomach with water, unless otherwise advised.
Side Effects:
Common:
Nausea, vomiting, diarrhea
Headache, dizziness
Stomach pain
Serious:
Increased risk of infections (fever, sore throat)
Low blood cell counts (anemia, leukopenia, thrombocytopenia)
Increased risk of certain cancers (skin and lymphoma) with long-term use
Allergic reactions (rash, swelling, breathing difficulty)
---
Warnings & Precautions:
Not safe in pregnancy – can cause birth defects. Effective contraception is required during and after treatment.
Avoid in patients with severe gastrointestinal disease or bone marrow suppression.
Increases risk of infection; avoid contact with sick individuals.
Live vaccines should not be taken during treatment.
Requires regular blood monitoring (kidney function, liver function, blood counts).
