Description :
Forxiga contains Dapagliflozin, a sodium-glucose co-transporter 2 (SGLT2) inhibitor. It works by helping the kidneys remove excess glucose through urine, thereby lowering blood sugar levels in patients with type 2 diabetes mellitus. Beyond glucose control, Forxiga is also used to treat chronic heart failure (with reduced or preserved ejection fraction) and chronic kidney disease, reducing the risk of hospitalization and disease progression.
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Dosage (Adults)
Type 2 Diabetes: 10 mg once daily in the morning, with or without food.
Heart Failure (HFrEF/HFpEF): 10 mg once daily.
Chronic Kidney Disease: 10 mg once daily.
> Not indicated for type 1 diabetes or diabetic ketoacidosis. Dose adjustments may be required for kidney impairment.
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Side Effects
Common:
Increased urination
Urinary tract infections (UTIs)
Genital yeast infections (thrush)
Thirst, dry mouth
Dizziness or low blood pressure
Serious:
Diabetic ketoacidosis (DKA): nausea, vomiting, abdominal pain, breathing difficulty
Severe urinary/genital infections (rare)
Dehydration and kidney function decline
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Warnings & Precautions
Not for patients with severe kidney impairment or on dialysis.
Maintain adequate hydration to reduce risk of dehydration and low blood pressure.
Monitor kidney function regularly during treatment.
Use with caution if combined with insulin or sulfonylureas (risk of low blood sugar).
Avoid during pregnancy and breastfeeding unless prescribed.
