Erythropoietin Injection (EPO)
Description:
Erythropoietin injection is a medication used to stimulate the production of red blood cells. It contains erythropoietin (EPO), a glycoprotein hormone normally produced by the kidneys, which promotes red blood cell formation in the bone marrow.
Uses / Indications:
Treatment of anemia associated with chronic kidney disease (CKD).
Management of anemia in patients receiving chemotherapy.
Prevention and treatment of anemia in certain patients scheduled for major surgery.
Supportive therapy in patients with HIV/AIDS receiving zidovudine.
How It Works:
Erythropoietin binds to receptors in the bone marrow, stimulating precursor cells to mature into red blood cells, thereby increasing hemoglobin levels and improving oxygen delivery to tissues.
Dosage Form:
Injection (available as vials or prefilled syringes for subcutaneous or intravenous administration).
Strengths may vary (e.g., 2,000 IU, 4,000 IU, 10,000 IU, 40,000 IU).
Common Side Effects:
Headache, nausea, injection site pain.
High blood pressure.
Joint or bone pain.
Rarely: blood clots, seizures.
Precautions:
Use under medical supervision only.
Regular monitoring of hemoglobin levels is required.
Caution in patients with uncontrolled hypertension, heart disease, or history of stroke.