Amartem Softgel 80/480 is a high-strength combination antimalarial medicine containing Artemether 80 mg and Lumefantrine 480 mg. It is used in the treatment of uncomplicated malaria caused by Plasmodium falciparum, including resistant strains. The softgel form enhances absorption and patient compliance, especially for those who struggle with tablets. Artemether provides rapid parasite clearance, while Lumefantrine prevents relapse.
Dosage (Adults & Children ≥35 kg)
Adults & Children (≥35 kg): 1 softgel capsule twice daily (morning & evening) for 3 days (total 6 doses).
Children
> Must always be taken with fatty food or milk for better absorption.
Side Effects
Common:
Headache, dizziness
Nausea, vomiting, diarrhea
Abdominal pain, loss of appetite
Weakness, fatigue
Serious (rare):
Irregular heartbeat (QT prolongation)
Severe allergic reaction (rash, swelling, breathing difficulty)
Liver problems (jaundice, dark urine)
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Warnings & Precautions
Not recommended in severe malaria or first trimester of pregnancy (unless no alternative).
Use with caution in patients with heart disease, liver or kidney impairment.
Avoid combining with grapefruit juice or medicines affecting heart rhythm.
Complete the full 3-day course even if symptoms improve.
Store in a cool, dry place, away from children.