Zidovudine + Lamivudine + Nevirapine (AZT + 3TC + NVP) is a fixed-dose combination of antiretroviral drugs used in the management of HIV infection. This triple therapy helps to reduce the viral load, increase CD4 cell count, and improve the immune system’s ability to fight infections. It is commonly used as a first-line regimen in Nigeria under national HIV treatment programs.
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Dosage
Standard adult dose: 1 tablet twice daily, or as directed by a healthcare professional.
Pediatric and dose adjustments should be strictly based on a doctor’s prescription.
Must be taken regularly at the same time daily for best results.
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Uses
Treatment of HIV-1 infection in adults and children.
Helps to suppress viral replication.
Reduces the risk of HIV-related complications such as opportunistic infections.
Improves quality of life and life expectancy in HIV patients.
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Side Effects
Common side effects may include:
Headache, dizziness, fatigue
Nausea, vomiting, diarrhea
Rash, skin reactions (especially with nevirapine)
Anemia or low blood counts (Zidovudine-related)
Rare but serious: Liver problems, severe skin reactions
⚠️ Always consult a healthcare professional if side effects become severe.
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Precautions
Not recommended for patients with severe liver or kidney impairment.
Regular blood tests may be required to monitor liver function and blood counts.
Should not be taken with other medicines that strongly interact with antiretrovirals.
Pregnant or breastfeeding women should use only under medical supervision.
