Sorafenib 200mg is a targeted cancer therapy medication classified as a tyrosine kinase inhibitor (TKI). It works by blocking cancer cell growth and preventing the formation of blood vessels that supply tumors. Sorafenib is commonly prescribed in the treatment of certain types of liver, kidney, and thyroid cancers.
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Uses:
Treatment of hepatocellular carcinoma (HCC) – liver cancer
Treatment of advanced renal cell carcinoma (RCC) – kidney cancer
Treatment of differentiated thyroid carcinoma (DTC) that is resistant to radioactive iodine treatment
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Dosage & Administration:
Typical adult dose: 400mg daily (200mg twice a day), taken orally.
Tablets should be swallowed whole with water, without crushing or chewing.
Take at least 1 hour before or 2 hours after meals.
Dosage may be adjusted by a healthcare provider based on tolerance and response.
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Side Effects:
Common:
Diarrhea
Fatigue
Weight loss
Loss of appetite
Rash, hand-foot skin reaction
Serious but less common:
High blood pressure (hypertension)
Bleeding problems
Heart problems (chest pain, heart attack risk)
Severe liver problems
👉 Patients should seek immediate medical attention if they experience chest pain, severe bleeding, yellowing of the eyes/skin, or difficulty breathing.
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Precautions:
Not recommended during pregnancy or breastfeeding
Use with caution in patients with heart disease, hypertension, or liver problems
Avoid grapefruit or grapefruit juice (may increase drug levels in the body)
Inform your doctor of all other medications you are taking to prevent interactions
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Storage:
Store at room temperature (below 30°C).
Keep in a dry place away from moisture and light.
Keep out of reach of children.
