Sevoflurane is a volatile liquid anesthetic used for general anesthesia. It is administered by inhalation through a vaporizer during surgery to help patients fall asleep quickly and remain unconscious and pain-free. Sevoflurane has a rapid onset and recovery, making it widely used in both adult and pediatric surgeries.
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Dosage (General Use):
Induction (starting anesthesia): Typically 0.5% – 3% in oxygen, increased gradually.
Maintenance (during surgery): 0.5% – 3% with oxygen or a mixture of oxygen/nitrous oxide.
Exact dosage depends on age, weight, type of surgery, and patient condition.
(Must only be administered by trained anesthesiologists using a calibrated vaporizer.)
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Precautions & Warnings:
For hospital/clinical use only.
Use with caution in patients with liver disease, kidney impairment, or history of malignant hyperthermia.
May increase intracranial pressure; use carefully in patients with brain injury.
Not recommended in patients allergic to halogenated anesthetics.
Avoid prolonged or repeated exposure to prevent organ toxicity.
Pregnancy and breastfeeding: only under strict medical supervision.
Possible Side Effects:
Common: nausea, vomiting, headache, shivering, dizziness, cough.
Serious (rare): malignant hyperthermia, severe liver injury, irregular heartbeat, respiratory depression, seizures.
Prolonged use may affect kidney function.